O-Methyl Phosphorodichloridit

O-Methyl Phosphorodichloridit - Names and Identifiers

Name	methyl dichlorophosphite
Synonyms	Methoxydichlorophosphine methyl dichlorophosphite DICHLOROMETHOXY PHOSPHINE DICHLORO METHYL PHOSPHITE Methyl dichloridophosphite METHYL PHOSPHORODICHLORIDITE Methoxyphosphonous Dichloride O-Methyl Phosphorodichloridit methyl phosphorodichloridoite O-Methyl Phosphorodichloridite Phosphorodichloridousacidmethylester Phosphorodichloridous acid, methyl ester METHYL DICHLOROPHOSPHITE, TECHNICAL GRADE Methyl Dichlorophosphite [Phosphitylating Agent]
CAS	3279-26-3
EINECS	221-915-3
InChI	InChI=1/CH3Cl2OP/c1-4-5(2)3/h1H3

O-Methyl Phosphorodichloridit - Physico-chemical Properties

Molecular Formula	CH3Cl2OP
Molar Mass	132.91
Density	1.376 g/mL at 20 °C (lit.)
Melting Point	-91 °C (lit.)
Boling Point	93-95 °C (lit.)
Flash Point	104°F
Water Solubility	Reacts with water. Soluble in chloroform, dichloromethane and ethyl acetate.
Vapor Presure	66.3mmHg at 25°C
Appearance	liquid
Color	Colorless to Almost colorless
BRN	1697452
Storage Condition	−20°C
Stability	Flammable.
Sensitive	Moisture Sensitive
Refractive Index	n20/D 1.474(lit.)
MDL	MFCD00000524

O-Methyl Phosphorodichloridit - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	R10 - Flammable R14 - Reacts violently with water R34 - Causes burns R37 - Irritating to the respiratory system
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 2920 8/PG 2
WGK Germany	3
FLUKA BRAND F CODES	10-13-23
HS Code	29209090
Hazard Class	8
Packing Group	II

O-Methyl Phosphorodichloridit - Introduction

methyl dichlorophosphite is an organic compound with the chemical formula CH3OCl2P. It is a colorless liquid, insoluble in water at room temperature, but soluble in organic solvents such as ether and benzene.

methyl dichlorophosphite has a wide range of applications in organic synthesis. It can be used as a synthetic reagent of phosphine compounds for the synthesis of various organophosphorus compounds. In addition, it can also be used as an alkylating agent for phosphate esters for the synthesis of drugs, pesticides and other organic compounds.

A common method for preparing methyl dichlorophosphite is to react phosphine dichloride with methanol. The reaction conditions may be room temperature, and the reaction is promoted by an acid-base catalyst such as aluminum trichloride or the like.

Pay attention to safety when using methyl dichlorophosphite. It is an organic phosphine compound with certain toxicity and irritation. Contact with skin, eyes or inhalation of its vapors may cause irritation and injury. The operation should be carried out in a well-ventilated environment with appropriate protective equipment such as gloves, glasses and masks. At the same time, it should be stored in a sealed container, away from heat and fire sources. If ingested or inhaled, seek medical help immediately.

Last Update：2024-04-09 21:11:58